Thursday, 15th February Lorne Infection and Immunity 2018

Speaker: Dr Shima Hamidi
Title: “Fast and sensitive detection of comprehensive range of inflammation biomarkers.”

• Molecular mechanisms underlying Mycobacterium tuberculosis-host interactions  - Cui Hua Liu
• Immune Regulation of the Unfolded Protein Response in Infection - Sumaira Hasnain
• Salmonella Typhimurium employs SPI2 virulence factors to evade inflammasome activation in human macrophages - Damien Bierschenk
• Influenza A virus infection is exacerbated in a mouse model of chronic inflammatory lung disease - Belinda J Thomas
• The inflammasome adaptor ASC suppresses tumour cell apoptosis, independent of inflammation, via IL-18 in gastric cancer. - Virginie Deswaerte

• Pattern Recognition Receptor signaling in response to bacterial infection - Clare Bryant
• The importance of cGAMP horizontal transfer in DNA damage-driven inflammation - Michael Gantier
• Understanding TLR-induced Myddosome formation and signalling - Dominic De Nardo
• Characterisation of a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response - Rebecca Ambrose
• Mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and -7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation in innate immune cells - Kate E Lawlor
• Structural basis of signaling by cooperative assembly formation in innate immunity pathways - Thomas Ve

• Genome-Wide Approaches to Characterize Apicomplexan Parasites - Sebastian Lourido
• Host immunity and the emergence of antimalarial resistance - Freya Fowkes
• Liver-resident memory T cells can be harnessed for highly efficient protection against malaria - Daniel Fernandez-Ruiz
• NLRC5 plays a protective role in Helicobacter-induced inflammation and lymphoid tissue formation - Michelle Chonwerawong
• Molecular characterization of streptococcal superantigens from scarlet fever Streptococcus pyogenes emm12 clones associated with the scarlet fever outbreak in Hong Kong - Stephan Brouwer
• Staphylococcus aureus membrane vesicles are immunostimulatory and activate innate immune pathways - Natalie J Bitto
• Tenofovir alafenamide abrogates human T-leukemia virus 1 infection in a humanised mouse model of infection - James Cooney
• CRISPR/Cas9 screens identify novel host-pathogen interactions as potential drug targets for treatment of Burkholderia pseudomallei Melioidosis - Marcel Doerflinger
• Isolation of HIV heterologous neutralising antibody from cow vaccinated with HIV envelope gp140 - Behnaz Heydarchi
• Characterising the function of Legionella pneumophila effector proteins during host infection - pengfei li
• Unearthing new findings of the NLRP3 inflammasome using novel reporter mice - James Ong
• The molecular dissection of host manipulation by chronic Toxoplasma gondii - Simona Seizova
• Roles of the Dot/Icm effector proteins during Legionella pneumophila infection in macrophages - Rachelia R Wibawa
• Investigation of the mechanisms and functions of Henipavirus Matrix protein nucleolar targeting - Tianyue Zhao

• Dissecting the role of TNF signalling in Mycobacterium tuberculosis disease pathogenesis to identify novel therapeutic targets - Michael Stutz
• Nasal tissue resident memory CD8+ T cells prevent pulmonary influenza A virus infection - Angela Pizzolla
• Trained immunity: a memory for innate host defense - Mihai Netea

• The role of peroxisomes and the ISG viperin in modulation of the MAVS mediated antiviral response - Michael Beard
• Changes in alveolar macrophage function following airway allergen exposure - Rob Bischof
• Characterization of the putative cysteine protease effectors, OspD2 and OspD3, from Shigella species. - Yogeswari Chandran
• Characterization of the role of type I Interferon signalling in intestinal inflammation - Eveline D de Geus
• Spatial organisation of protein export in malaria parasite blood stages. - Paul Gilson
• New insights into the regulation and inhibition of bacterial aggregation/biofilm formation - Begoña Heras
• DNA transfer occurs in Gram-negative bacteria via outer membrane vesicles - Ella L Johnston
• Fc functional antibodies asset in the control of humans with severe H7N9 and seasonal influenza - Stephen Kent
• Examination of the role of activin A and resident testicular cell types in fibrosis following experimental autoimmune orchitis (EAO) in mice - Christine A Kleinert
• Characterisation of E2-DHBVS virus-like particles as a HCV vaccine candidate - Joey McGregor
• Deciphering the in vivo role of necroptosis in bacterial gut infection - Jaclyn S Pearson
• Evaluation of bismuth derived chemical compounds as antiviral agents against dengue - Babu Ramanathan
• Understanding the mechanisms involved in host permissivity to Ross River and Barmah Forest viruses. - Penny Rudd
• How Salmonella maintains the copper homeostasis?  - Pramod Subedi
• Modulation of endoplasmic reticulum stress to alleviate respiratory viral infection by blocking interleukin-22 - Ran Wang
• Subunit vaccines based on stabilisation of trimeric, pre-fusion influenza HA elicits cross-protection between highly divergent influenza A viruses - Paul Young
• Characterisation of Helicobacter pylori outer membrane vesicles produced during different stages of bacterial growth. - Lauren Zavan